Created in 1840, the "Liqueur de Santé" is the first liqueur made from the original recipe of the Elixir Végétal de la Grande Chartreuse. It was so popular that Father Garnier, attorney and responsible for the liqueurs at the time, later decided to officially name it 'Chartreuse Verte', and registered the “Chartreuse” mark in 1852. It is still produced and manufactured today by the Chartreux Fathers in their Aiguenoire distillery in Entre-Deux-Guiers (Isère - France).

'Chartreuse Verte' derives its unique character from its natural color, its power and its aromatic complexity from 130 plants, flowers, bark, roots and spices.
Its development requires several weeks of work and is done in various stages:
- Grinds made by the monks in the plant room at the Grande Chartreuse monastery.
- Distillation to obtain the aroma.
- Different types of maceration that extract the active ingredients from the plants and give the liquor its natural color.
It then ages for a long time in oak casks before being bottled, and continues to evolve and develop its complexity in the bottle.